Pharmacological properties Pharmacodynamics dihydropyridine derivative – blocker “slow” calcium channels II generation, has antianginal and hypotensive action. Communicating with the dihydropyridine receptor, blocks calcium channels reduces the transmembrane passage of calcium ions into the cell (mainly in vascular smooth muscle cells than cardiac myocytes). Antianginal effect is due to the expansion of the coronary and peripheral arteries and arterioles: angina reduces the severity of myocardial ischemia; expanding peripheral arterioles, decreases total peripheral vascular resistance, decreases the preload on the heart, reducing myocardial oxygen demand. Expanding the major coronary arteries and arterioles in the unaltered and ischemic myocardial areas, increases the ...
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Mesterolone, also known as Proviron, is an androgenic anabolic steroid that was first created in 1966 and established for medical use a year later. The steroid was used to treat of low testosterone levels, androgen deficiency in males (hypogonadism), anemia, to support male fertility, and delayed puberty in boys. Proviron has no estrogenic effects and does not aromatize into estrogen. It even has aromatase inhibiting properties and therefore can be used to treat breast tenderness or gynecomastia in men. The steroid is also strongly androgenic, weakly anabolic and not progestogenic in any way. See our article about Cypionate vs Enanthate BUY ...
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